Skip to main content

Reducing intake of one amino acid improves longevity & health in mice

Studies into the benefits of protein-restricted diets have shown that lower protein consumption is associated with a decreased risk of age-related diseases and mortality and improved metabolic health. Now, exploring alternatives to calorie-restricting diets, researchers at the University of Wisconsin-Madison have found that reducing the intake of a single amino acid in mice extended their lifespan, making them leaner, less frail, and less susceptible to cancer.

“We like to say a calorie is not just a calorie,” said Dudley Lamming, corresponding author of the study. “Different components of your diet have value and impact beyond their function as a calorie, and we’ve been digging in on one component that many people may be eating too much of.”