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Antibodies to opioids discovered in long-term users

“Opioid use disorder and opioid overdoses continue to be a major epidemic in this country,” says Cody Wenthur, from the University of Wisconsin–Madison. “A relatively new therapeutic approach entering clinical trials is what in shorthand we call an opioid vaccine, where the immune system generates a response against the drugs. But for this approach to be successful, we need to identify the people who would benefit from that approach.”